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Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
20 μg | ¥ 1,870 | 20日内发货 | |
100 μg | ¥ 2,970 | 20日内发货 |
生物活性 | Measured by its binding ability in a functional ELISA. Immobilized Human MAGEA4 at 2 μg/mL can bind anti-MAGEA4 recombinant antibody, the EC 50 is 30.33-43.10 ng/mL. |
产品描述 | Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-10xHis |
蛋白编号 | P43358 |
别名 | Melanoma-associated antigen 4,MAGE-X2 antigen,MAGEA4,MAGE-41 antigen,MAGE-4 antigen,Cancer/testis antigen 1.4 |
氨基酸序列 | MSSEQKSQHCKPEEGVEAQEEALGLVGAQAPTTEEQEAAVSSSSPLVPGTLEEVPAAESAGPPQSPQGASALPTTISFTCWRQPNEGSSSQEEEGPSTSPDAESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRCFPVIFGKASESLKMIFGIDVKEVDPASNTYTLVTCLGLSYDGLLGNNQIFPKTGLLIIVLGTIAMEGDSASEEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQENYLEYRQVPGSNPARYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAALLEEEEGV |
蛋白构建 | 1-317 aa |
蛋白纯度 | > 90% as determined by SDS-PAGE. |
分子量 | 36.7 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0 |
复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis. |
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