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Ganoderic acid S, a positional isomer of ganoderic acids, can be isolated from the fermented mycelia of Ganoderma lucidum. It can induce apoptosis in HeLa cells through the mitochondria pathway [1].
Ganoderic acid S, a positional isomer of ganoderic acids, can be isolated from the fermented mycelia of Ganoderma lucidum. It can induce apoptosis in HeLa cells through the mitochondria pathway [1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 待询 | |
50 mg | 询价 | 待询 |
产品描述 | Ganoderic acid S, a positional isomer of ganoderic acids, can be isolated from the fermented mycelia of Ganoderma lucidum. It can induce apoptosis in HeLa cells through the mitochondria pathway [1]. |
体外活性 | Ganoderic acid S 在不同浓度下 (0, 39.1, 97.7 μM; 12 h) 对 HeLa 细胞进行处理,结果显示导致细胞周期在 S 期停滞 [1]。此外,Ganoderic acid S 会剂量依赖性地诱导线粒体膜电位崩溃,并促使细胞色素 c 大量从线粒体释放到 HeLa 细胞的胞质溶胶中 [1]。这些研究通过对 HeLa 细胞进行细胞周期分析确认,具体方法包括用不同浓度的 Ganoderic acid S 处理细胞 12 小时,并观察到细胞周期在 S 期的停滞现象。 |
分子量 | 512.72 |
分子式 | C32H48O5 |
CAS No. | 103963-38-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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