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NRG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.5 kDa and the accession number is D9ZHP7.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μg | ¥ 4,460 | 5日内发货 | |
1 mg | ¥ 29,100 | 5日内发货 |
生物活性 | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
产品描述 | NRG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.5 kDa and the accession number is D9ZHP7. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | D9ZHP7 |
别名 | pro-NRG3,neuregulin 3,HRG3 |
蛋白构建 | A DNA sequence encoding the human NRG3 (ADK90021.1) (Glu282-Pro342) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Glu |
蛋白纯度 | > 95 % as determined by SDS-PAGE |
分子量 | 8.5 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. |
研究背景 | NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4. NRG3, a brain-enriched neurotrophin, undergoes alternative splicing and is implicated in several neurological disorders with developmental origins. It also promotes mammary differentiation during embryogenesis. NRG3 promotes early mammary morphogenesis and acts during specification of the mammary placode, an aggregate of epithelial cells that form during mid-embryogenesis. Diseases associated with NRG3 include Schizophrenia and Schizoaffective Disorder. |
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