Tetrachlorohydroquinone

Name: Tetrachlorohydroquinone
Brand: TargetMol
SKU: T36507
Rating: 4.5 (1 reviews)

还可以

产品编号 T36507Cas号 87-87-6

Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes.

Tetrachlorohydroquinone

还可以

产品编号 T36507Cas号 87-87-6

规格	价格	库存
1 g	待估	35日内发货
5 g	待估	35日内发货
10 g	待估	35日内发货

大包装 & 定制

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

联系我们获取更多批次信息

资源下载

产品操作手册

产品介绍

生物活性

产品描述	Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes.
体内活性	In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.

化学信息

分子量	247.89
分子式	C₆H₂Cl₄O₂
CAS No.	87-87-6

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMF: 30 mg/mL (121.02 mM), Sonication is recommended.

Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL (2.02 mM), Sonication is recommended.

DMSO: 30 mg/mL (121.02 mM), Sonication is recommended.

Ethanol: 30 mg/mL (121.02 mM), Sonication is recommended.

溶液配制表

DMF/DMSO/Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.8068 mL	4.0340 mL	8.0681 mL	40.3405 mL
10 mM	0.4034 mL	2.0170 mL	4.0340 mL	20.1702 mL
20 mM	0.2017 mL	1.0085 mL	2.0170 mL	10.0851 mL
50 mM	0.0807 mL	0.4034 mL	0.8068 mL	4.0340 mL
100 mM	0.0403 mL	0.2017 mL	0.4034 mL	2.0170 mL