Tilapia piscidin 3, an antimicrobial peptide, exhibits antibacterial properties effective against both gram-positive and gram-negative bacteria. It has demonstrated minimum inhibitory concentrations (MICs) of 2.44 µg/mL for V. vulnificus 204 and V. alginolyticus, 9.78 µg/mL for S. agalactiae 819, 19.55 µg/mL for E. faecalis BCRC 10066, and 0.61 µg/mL for S. agalactiae BCRC 10787. Additionally, it presents hemolytic activity on fish red blood cells [1].