Real Thiol

Name: Real Thiol
Brand: TargetMol
SKU: T12776L
Rating: 4.5 (1 reviews)

还可以

产品编号 T12776LCas号 2280796-90-7

Real Thiol, a reversible reaction-based fluorescent probe, can quantitatively monitor the real-time glutathione dynamics in living cells.

Real Thiol

还可以

产品编号 T12776LCas号 2280796-90-7

Real Thiol, a reversible reaction-based fluorescent probe, can quantitatively monitor the real-time glutathione dynamics in living cells.

规格	价格	库存	数量
5 mg	¥ 7,014	期货

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产品介绍

生物活性

产品描述

Real Thiol, a reversible reaction-based fluorescent probe, can quantitatively monitor the real-time glutathione dynamics in living cells.

体外活性

Real Thiol (RT) shows ratiometric fluorescence responses with a wide dynamic range when reacting with Glutathione (GSH). Real Thiol and its GSH adduct (RT-GSH) show fluorescence maxima at 487 and 562?nm with excitation wavelengths at 405 and 488?nm, respectively. The Kd for the reaction between Real Thiol and GSH is 3.7?mM. The wide dynamic range of Real Thiol (1 to 10?mM) allows for monitoring of the GSH level changes in both directions in living cells. 10% of Real Thiol reacts with thiolated proteins while 90% of Real Thiol reacts with GSH [1].

化学信息

分子量	411.37
分子式	C₂₀H₁₇N₃O₇
CAS No.	2280796-90-7
密度	1.599 g/cm3 (Predicted)

储存&溶解度

存储

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 101 mg/mL (245.53 mM)

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4309 mL	12.1545 mL	24.3090 mL	121.5451 mL
5 mM	0.4862 mL	2.4309 mL	4.8618 mL	24.3090 mL
10 mM	0.2431 mL	1.2155 mL	2.4309 mL	12.1545 mL
20 mM	0.1215 mL	0.6077 mL	1.2155 mL	6.0773 mL
50 mM	0.0486 mL	0.2431 mL	0.4862 mL	2.4309 mL
100 mM	0.0243 mL	0.1215 mL	0.2431 mL	1.2155 mL