PSMA Protein, Human, Recombinant (Improved, His)

产品编号 TMPY-07132

PSMA Protein, Human, Recombinant (Improved, His) is expressed in CHO Cells. The accession number is Q04609-1.

PSMA Protein, Human, Recombinant (Improved, His)

产品编号 TMPY-07132

PSMA Protein, Human, Recombinant (Improved, His) is expressed in CHO Cells. The accession number is Q04609-1.

规格	价格	库存	数量
50 μg	¥ 3,170	期货
1 mg	询价	期货

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产品信息

生物活性	1. Immobilized PSMA Protein, Human, Recombinant (Improved, His) (Cat#TMPY-07132) at 1 μg/mL (100 μL/well) can bind Anti-PSMA Antibody, the EC50 is 5-15 ng/mL. 2. Measured by its ability to hydrolyze the substrate N-acetyl-L-Asp-L-Glu into N-acetyl-L-Asp and L-Glu. The L-Glu product is measured by fluorescence after its derivatization by ortho-phthaldialdehyde. The specific activity is >800 pmol/min/µg.
产品描述	PSMA Protein, Human, Recombinant (Improved, His) is expressed in CHO Cells. The accession number is Q04609-1.
种属	Human
表达系统	CHO Cells
标签	N-His
蛋白编号	Q04609-1
别名	PSMA,PSM,NAALAdase,NAALAD1,mGCP,GIG27,GCPII,GCP2,FOLH,FGCP
蛋白构建	A DNA sequence encoding the Human FOLH1 (NP_004467.1) (Lys44-Ala750) was expressed, with a polyhistidine tag at the N-terminus.
蛋白纯度	≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
分子量	84.29 kDa (predicted); 94.5 kDa (reducing contition)
内毒素	< 1.0 EU per μg protein as determined by the LAL method.
缓冲液	Lyophilized from sterile solution in MES, NaCl, trehalose, CaCl2, MgCl2 and ZnCl2, pH 6.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法	Please refer to the lot-specific COA.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

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