CHPG

Name: CHPG
Brand: TargetMol
SKU: T10809
Price: 118 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T10809Cas号 170846-74-9

CHPG is a selective agonist of mGluR5. In BV2 microglial cells, it attenuates SO2-induced oxidative stress and inflammation through the TSG-6/NF-κB pathway.

CHPG

还可以

产品编号 T10809Cas号 170846-74-9

CHPG is a selective agonist of mGluR5. In BV2 microglial cells, it attenuates SO2-induced oxidative stress and inflammation through the TSG-6/NF-κB pathway.

规格	价格	库存
5 mg	¥ 857	35日内发货
10 mg	¥ 1,520	35日内发货
50 mg	¥ 6,650	35日内发货

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产品介绍

生物活性

产品描述	CHPG is a selective agonist of mGluR5. In BV2 microglial cells, it attenuates SO2-induced oxidative stress and inflammation through the TSG-6/NF-κB pathway.
体外活性	CHPG (0.5?mM; 30?mins ) protects BV2 cells against SO2-induced apoptosis. CHPG (10-500?μM; 24?hours) significantly increases the cell viability and decreases the LDH release after SO2 derivatives treatment. CHPG (0.5?mM; 30?mins) treatment alone increases the expression of TSG-6 in both mRNA and protein levels [1].
体内活性	CHPG (injection; 250 nM; for 7 days) reduces significantly cerebral lesion volume [2].