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TargetMol | Compound Library

抗癌化合物库现货

Anti-Cancer Compound Library

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产品编号 L2100

在过去的几十年中癌症的研究和治疗取得了巨大的成功,但癌症仍然是人类面临的巨大挑战,给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征,表现出无限的增殖潜能,维持自身生长信号的持续稳定,逃避应激信号(例如治疗药物)诱导的细胞凋亡,刺激血管生长,为肿瘤提供营养,同时逃避免疫系统防御和诱导局部慢性炎症,发挥其侵袭和转移能力,表现出异常的代谢活动,并通过突变和表观遗传机制显著改变全基因组的稳定性。 我们根据上述癌细胞显著不同的特征和异常的代谢活动,精心筛选了 8700 个肿瘤相关的小分子化合物,这些化合物都是调节肿瘤细胞代谢、增殖、侵袭、转移通路上的小分子,可用于肿瘤相关的研究以及抗肿瘤药物的筛选,可用于高通量、高内涵筛选。

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产品编号 L2100

抗癌化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 8700种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
  • 产品经过临床验证和临床实验,具有生物安全保障和一定的生物活性;
  • 是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具;?
  • 靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS检测技术保证产品高纯度和高质量,减少假阳性发生概率。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

Apoptosis
Autophagy
5-HT Receptor
Endogenous Metabolite
Antibacterial
COX
NF-κB
Adrenergic Receptor
DNA/RNA Synthesis
CDK
Dopamine Receptor
PI3K
EGFR
Potassium Channel
Reactive Oxygen Species
Histamine Receptor
Calcium Channel
P450
VEGFR
Antibiotic
Sodium Channel
JAK
GABA Receptor
HDAC
Parasite
PPAR
TRP/TRPV Channel
mTOR
GPR
AChR
ERK
Akt
Antifungal
Src
Prostaglandin Receptor
HIV Protease
Wnt/beta-catenin
FLT
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Estrogen Receptor/ERR
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STAT
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Dehydrogenase
Raf
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BCL
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c-Kit
c-Met/HGFR
Androgen Receptor
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Cannabinoid Receptor
Ferroptosis
Bcr-Abl
Histone Methyltransferase
HSP
PKC
ATPase
Sirtuin
MMP
TGF-beta/Smad
IL Receptor
Aurora Kinase
Ras
PDE
ALK
JNK
MAPK
Kras
Phosphatase
HER
NO Synthase
Tyrosine Kinases
MEK
Mitophagy
P-gp
ROCK
DUB
IκB/IKK
ADC Cytotoxin
p53
Serine/threonin kinase
SARS-CoV
Lipoxygenase
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ROS
HIF/HIF Prolyl-Hydroxylase
DNA-PK
S1P Receptor
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P2X Receptor
HSV
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PKA
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PAI-1
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p97
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Angiotensin-converting Enzyme (ACE)
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RXFP receptor

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