HOE-S 785026 trihydrochloride is a live cell labeling dye that binds nucleic acids by binding to the minor groove in DNA double strands. HOE-S 785026 trihydrochloride tends to bind to A/T-rich DNA strands (fluorescence is significantly enhanced by A/T-rich double-stranded DNA).HOE-S 785026 trihydrochloride crosses cell membranes and binds to living or immobilized cells.The fluorescence intensity of HOE-S 785026 trihydrochloride increases as the pH of the solution increases. HOE-S 785026 trihydrochloride crosses cell membranes and binds to living or immobilized cells. trihydrochloride fluorescence intensity increases as the pH of the solution is increased.