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RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1].
RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 1,450 | 5日内发货 | |
25 mg | ¥ 9,160 | 6-8周 | |
50 mg | ¥ 11,900 | 6-8周 | |
100 mg | ¥ 17,400 | 6-8周 |
产品描述 | RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1]. |
别名 | RNF5 inhibitor inh-02 |
分子量 | 384.5 |
分子式 | C23H20N4S |
CAS No. | 324579-65-9 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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