The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG expression independently predicts poorer prognosis in patients with EOC. Ectopic overexpression of GMFG contributes to the malignant biological behavior of ovarian cancer cells.
生物活性 | Testing in progress |
产品描述 | The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG expression independently predicts poorer prognosis in patients with EOC. Ectopic overexpression of GMFG contributes to the malignant biological behavior of ovarian cancer cells. |
种属 | Human |
表达系统 | E. coli |
标签 | N-His |
蛋白编号 | O60234 |
别名 | glia maturation factor, γ, glia maturation factor, gamma, GMF-γ, GMF-GAMMA |
蛋白构建 | Human GMFG (O60234) (Met1-Arg142) |
蛋白纯度 | > 85 % as determined by SDS-PAGE |
分子量 | 19 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells. GMFG expression independently predicts poorer prognosis in patients with EOC. Ectopic overexpression of GMFG contributes to the malignant biological behavior of ovarian cancer cells. |
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GMF gamma/GMFG Protein, Human, Recombinant (His) glia maturation factor, γ glia maturation factor, gamma GMF-γ GMF-GAMMA recombinant recombinant-proteins proteins protein