GSN Protein, Human, Recombinant (mFc)

Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some reaseraches show that gelsolin can act as a transcriptional cofactor in signal transduction and its own expression and function can be influenced by epigenetic changes. The difference in the expression levels of cytoplasmic and plasma gelsolin suggests that these two different forms of gelsolin may play different roles after cardiac injury. Plasma gelsolin, as an important component of the EASS, may have evolved to rapidly clear actin filaments from the circulation that are released by injured or dead cells.

规格	价格/CNY		数量
10 μg	￥ 1,020	5日内发货
50 μg	￥ 3,050	5日内发货
500 μg	￥ 15,400	5日内发货
1 mg	￥ 23,100	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,020

5日内发货

50 μg

￥ 3,050

5日内发货

500 μg

￥ 15,400

5日内发货

1 mg

￥ 23,100

5日内发货

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-mFc
蛋白编号	P06396
别名	ADF, Actin-depolymerizing factor, Brevin, Gelsolin, GSN, AGEL
氨基酸序列	Ala28-Ala782
蛋白构建	Ala28-Ala782
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	115-125 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 5% Trehalose, 0.1% Triton X-100, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some reaseraches show that gelsolin can act as a transcriptional cofactor in signal transduction and its own expression and function can be influenced by epigenetic changes. The difference in the expression levels of cytoplasmic and plasma gelsolin suggests that these two different forms of gelsolin may play different roles after cardiac injury. Plasma gelsolin, as an important component of the EASS, may have evolved to rapidly clear actin filaments from the circulation that are released by injured or dead cells.

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Mass (in vial)

Desired Reconstitution Concentration

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GSN Protein, Human, Recombinant (mFc)

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