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PAMP-12 (unmodified)为有效的MRGPRX2 (MrgX2)激动剂,其EC50值为20-50 nM。作为内源性肽,它能够通过抑制交感神经末梢和肾上腺嗜铬细胞的儿茶酚胺分泌来引发低血压。
PAMP-12 (unmodified)为有效的MRGPRX2 (MrgX2)激动剂,其EC50值为20-50 nM。作为内源性肽,它能够通过抑制交感神经末梢和肾上腺嗜铬细胞的儿茶酚胺分泌来引发低血压。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from sympathetic nerve endings and adrenal chromaffin cells [1]. |
分子量 | 1619.91 |
分子式 | C77H118N24O15 |
CAS No. | 929905-12-4 |
存储 | keep away from moisture | Shipping with blue ice. |
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