BMS-986118

Name: BMS-986118
Brand: TargetMol
SKU: T26868
Price: 415 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T26868Cas号 1610562-74-7

别名 BMS 986118

BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia.

BMS-986118

还可以

产品编号 T26868 别名 BMS 986118Cas号 1610562-74-7

规格	价格	库存
25 mg	¥ 19,400	10-14周
50 mg	¥ 25,800	10-14周
100 mg	¥ 33,500	10-14周

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产品介绍

生物活性

产品描述	BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabetes. Activation of GPR40 by partial agonists elicits insulin secretion only in the presence of elevated blood glucose levels, minimizing the risk of hypoglycemia.
靶点活性	FFA1/GPR40:0.07 µM (IC50)
别名	BMS 986118