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Lepidiline A (Macaline A) 是一种具有抗炎症活性的黄酮木质素。Lepidiline A 对HL-60细胞具有细胞毒活性,IC50值为 32.3 μM。它是从芸苔科植物Lepidium meyenii Walpers 的活性成分,可改善小鼠内源性性激素的平衡,提高果蝇的繁殖力。Lepidiline A 靶向HSD17B1基因的机制来增强酶的活性,提高性激素的生物转化效率,提高生殖能力。Lepidiline A 具有抗癌活性。
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Lepidiline A (Macaline A) 是一种具有抗炎症活性的黄酮木质素。Lepidiline A 对HL-60细胞具有细胞毒活性,IC50值为 32.3 μM。它是从芸苔科植物Lepidium meyenii Walpers 的活性成分,可改善小鼠内源性性激素的平衡,提高果蝇的繁殖力。Lepidiline A 靶向HSD17B1基因的机制来增强酶的活性,提高性激素的生物转化效率,提高生殖能力。Lepidiline A 具有抗癌活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 455 | 现货 | |
5 mg | ¥ 987 | 现货 | |
10 mg | ¥ 1,820 | 现货 | |
25 mg | ¥ 2,960 | 现货 | |
50 mg | ¥ 4,390 | 现货 | |
100 mg | ¥ 6,180 | 现货 |
产品描述 | Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a plant in the brassica family, and improves the balance of endogenous sex hormones in mice and the fectility of fruit flies. Lepidiline A targets HSD17B1 gene to enhance enzyme activity, improve the efficiency of sex hormone bioconversion, and improve reproductive ability. Lepidiline A has anticancer activity. |
靶点活性 | Cytotoxic activity (HL-60 cells):32.3 μM |
别名 | 玛卡多酚A, Macaline A |
分子量 | 312.84 |
分子式 | C19H21ClN2 |
CAS No. | 596093-98-0 |
Smiles | [Cl-].Cc1c(C)[n+](Cc2ccccc2)cn1Cc1ccccc1 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 45 mg/mL (143.84 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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