Clusterin Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is (33-45) and (60-85) KDa and the accession number is P10909.

Human

HEK293 Cells

TRPM-2,Testosterone-Repressed Prostate Message 2,SGP-2,NA1/NA2,KUB1,Ku70-Binding Protein 1,Complement-Associated Protein SP-40,Complement Cytolysis Inhibitor,Clusterin,CLU,CLI,Apolipoprotein J,Apo-J,APOJ,Aging-Associated Gene 4 Protein,AAG4,40

Asp23-Glu449

Asp23-Glu449

Greater than 90% as determined by reducing SDS-PAGE. (QC verified)

Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.