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Poloppin
还可以产品编号 T24652Cas号 683808-78-8
Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.
Poloppin
还可以产品编号 T24652Cas号 683808-78-8
Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 455 | 35日内发货 | |
| 5 mg | ¥ 1,340 | 35日内发货 | |
| 10 mg | ¥ 2,460 | 35日内发货 | |
| 25 mg | ¥ 5,600 | 35日内发货 |
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| 产品描述 | Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells. |
| 靶点活性 | PLK:26.9 μM (IC50), Protein-Protein interaction via the Polo-box domain (PBD):26.9 μM (Kd) |
| 分子量 | 438.24 |
| 分子式 | C20H15BrF3NO2 |
| CAS No. | 683808-78-8 |
| 密度 | 1.45 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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