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ECM1 Protein, Human, Recombinant (His)

产品编号 TMPY-07013

ECM1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q16610-1.

ECM1 Protein, Human, Recombinant (His)

ECM1 Protein, Human, Recombinant (His)

产品编号 TMPY-07013
ECM1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q16610-1.
规格价格库存数量
100 μg
¥ 3,430
期货
1 mg 询价 期货
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产品信息

生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
ECM1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q16610-1.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号Q16610-1
别名
URBWD
蛋白构建
A DNA sequence encoding the human ECM1 isoform 1 (NP_004416.2)(Met 1-Glu 540) was expressed with a C-terminal polyhistidine tag.
蛋白纯度
≥ 90% as determined by SDS-PAGE
分子量60.2 kDa (predicted); 80-90 kDa (reducing contition, due to glycosylation)
内毒素< 1.0 EU per μg of the protein as determined by the LAL method
缓冲液Lyophilized from sterile PBS, pH 7.2. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法
Please refer to the lot-specific COA.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.

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