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IL-20RB Protein, Human, Recombinant (His)

产品编号 TMPY-05559

别名: interleukin 20 receptor β, interleukin 20 receptor beta, IL-20R2, DIRS1, FNDC6

IL-20RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q6UXL0-1.

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IL-20RB Protein, Human, Recombinant (His)

规格	价格/CNY		货期	数量
50 μg	￥ 2,270		5日内发货
1 mg	￥ 24,900		5日内发货

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生物活性	Testing in progress
产品描述	IL-20RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q6UXL0-1.

种属	Human
表达系统	Baculovirus Insect Cells
标签	C-His
蛋白编号	Q6UXL0-1
别名	interleukin 20 receptor β, interleukin 20 receptor beta, IL-20R2, DIRS1, FNDC6
蛋白构建	The Human IL20RB (NP_653318.2) (Met1-Ala230) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度	10 μl/Test, 0.1 mg/ml
分子量	23.9 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Aqueous solution containing 0.5% BSA and 0.03% Proclin 300
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20, and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA form a heterodimeric receptor for interleukin-20.

参考文献

1. Zhu H,et al.(2009) Expression pattern of mda-7/IL-24 receptors in liver cancer cell lines. Hepatobiliary Pancreat Dis Int. 8(4):402-6. 2. Logsdon NJ,et al.(2012) Purification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 68(Pt 1):89-92. 3. Kingo K,et al.(2008) Association analysis of IL20RA and IL20RB genes in psoriasis. Genes Immun. 9(5):445-51.

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Keywords

IL-20RB Protein, Human, Recombinant (His) DIRS 1 interleukin 20 receptor β DIRS-1 interleukin 20 receptor beta FNDC-6 FNDC 6 IL-20R2 DIRS1 FNDC6 recombinant recombinant-proteins proteins protein

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