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Batrachotoxin (BTX) 存在于哥伦比亚箭毒蛙 (Phyllobates aurotaenia) 的皮肤中,是一种功能强大的神经毒素兼心脏毒素。其通过激活细胞膜上的电压门控钠离子通道 (sodium channel),阻断这些通道的正常关闭功能,从而使钠离子持续流入细胞,导致细胞持续去极化。
Batrachotoxin (BTX) 存在于哥伦比亚箭毒蛙 (Phyllobates aurotaenia) 的皮肤中,是一种功能强大的神经毒素兼心脏毒素。其通过激活细胞膜上的电压门控钠离子通道 (sodium channel),阻断这些通道的正常关闭功能,从而使钠离子持续流入细胞,导致细胞持续去极化。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Batrachotoxin (BTX), a potent neurotoxin and cardiotoxin, is found in the skin of the Colombian dart frog (Phyllobates aurotaenia). As an activator of sodium channels (sodium channel), it interferes with normal sodium channel closure by binding to voltage-gated sodium channels (sodium channel) on the cell membrane. This interaction causes a continuous influx of sodium ions into the cells, leading to persistent depolarization. |
别名 | BTX |
分子量 | 538.67 |
分子式 | C31H42N2O6 |
CAS No. | 23509-16-2 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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