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FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
产品编号 TMPK-00619
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971.
FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
产品编号 TMPK-00619
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 5,930 | 5日内发货 | |
| 500 μg | ¥ 23,700 | 5日内发货 | |
| 1 mg | ¥ 39,500 | 5日内发货 |
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生物活性
| 生物活性 | Immobilized Anti-FcRH5 Antibody, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FcRH5, His Tag with the EC50 of 46.0ng/ml determined by ELISA. |
| 产品描述 | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | AAK93971 |
| 别名 | IFGP5,CD307,FCRH5MGC119593,FLJ00397,DKFZp667E2019,BXMAS1MGC119592,DKFZp667F216,FcRH5,FcR-like protein 5,CD307e,FcRL5,BXMAS1,FLJ00333 |
| 蛋白构建 | Gln16-Gly851 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC |
| 分子量 | 92.38 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result. |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 100 mM Arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 研究背景 | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
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