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PAO-Nap
还可以产品编号 T36399Cas号 1613402-20-2
PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].
PAO-Nap
还可以产品编号 T36399Cas号 1613402-20-2
PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1].
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥ 2,397 | 期货 | |
| 10 mg | ¥ 3,855 | 期货 |
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生物活性
化学信息
| 产品描述 | PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1]. |
| 体外活性 | PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1]. |
| 分子量 | 509.394 |
| 分子式 | C24H24AsN3O5 |
| CAS No. | 1613402-20-2 |
| 密度 | no data available |
储存&溶解度
| 存储 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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