Swiss Prot Protein Targets and PDB X Ray Structure Search: ACE2, PLpro, 3CLP Training Sets ChEMBL 25, PubMed, Current Patent Literature (CAS, Integrity)
ChemDiv presents a brand new library – Opportunistic Pathogens of Immunocompromised Hosts Annotated Library (OPICH library), which consists of over 2,500 compounds.
It is patently obvious that CNS activity (and trans-cellular permeability in general) is a complex function of physical chemical properties of molecules such as size, lipophilicity, hydrogen-bonding potential, charge, and conformation.