CD98 Protein, Human, Recombinant (mFc)

产品编号 TMPJ-00352

CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.

CD98 Protein, Human, Recombinant (mFc)

产品编号 TMPJ-00352

规格	价格	库存
10 μg	¥ 410	5日内发货
50 μg	¥ 1,270	5日内发货
500 μg	¥ 10,000	5日内发货
1 mg	¥ 15,100	5日内发货

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产品信息

生物活性	1. Loaded Anti-Human CD98 mAb-Fc on AHC Biosensor, can bind Human CD98-mFc with an affinity constant of <10^-3 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Human CD98-mFc at 2μg/ml (100 μl/well) can bind Anti-Human CD98 mAb . The ED50 of Anti-Human CD98 mAb is 1.34 ng/ml. (Regularly tested)
产品描述	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.
种属	Human
表达系统	HEK293 Cells
标签	N-mFc
蛋白编号	P08195
别名	Solute carrier family 3 member 2,SLC3A2,MDU1,Lymphocyte activation antigen 4F2 large subunit,CD98,4F2hc,4F2 cell-surface antigen heavy chain
氨基酸序列	Arg206-Ala630
蛋白构建	Arg206-Ala630
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	70-100 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis, invasiveness, and proliferation in addition to promoting malignant transformation of cells. Fibrotic progression in the liver could be linked to the activation of integrin αvβ1 via CD98. CD98’s role in T cell activation in which the TGF activation could also play a profibrotic role.

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重组蛋白稀释计算器
比活力计算器

技术支持

请阅读重组蛋白用户指南了解更多具体信息.

关键词

MDU 1 CD-98 CD 98 MDU-1