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C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect against IFN-γ-stimulated HepG2 cellular STAT1 phosphorylation.
C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect against IFN-γ-stimulated HepG2 cellular STAT1 phosphorylation.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥ 2,113 | 期货 |
产品描述 | C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect against IFN-γ-stimulated HepG2 cellular STAT1 phosphorylation. |
别名 | STAT3-IN-C188, Cpd-188, Cpd188, C-188, C 188 |
分子量 | 433.45 |
分子式 | C19H15NO7S2 |
CAS No. | 823828-18-8 |
密度 | 1.67 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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