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顶部生物活性储存和溶解信息计算器

Prostaglandin A2

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产品编号 T36542Cas号 13345-50-1
别名 Medullin

PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity.[1] At a 25 uM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase .[2] It has also been shown to act as a vasodilator with natriuretic properties.[3]

Prostaglandin A2
其他形式的 “Prostaglandin A2”:
8-iso Prostaglandin A2T36158474391-66-7
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Prostaglandin A2

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产品编号 T36542 别名 MedullinCas号 13345-50-1

PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity.[1] At a 25 uM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase .[2] It has also been shown to act as a vasodilator with natriuretic properties.[3]

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生物活性
产品描述
PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity.[1] At a 25 uM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase .[2] It has also been shown to act as a vasodilator with natriuretic properties.[3]
别名Medullin
化学信息
分子量334.45
分子式C20H30O4
CAS No.13345-50-1
密度1.103g/cm3
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度信息
DMF: 75 mg/mL (224.25 mM), Sonication is recommended.
DMSO: 50 mg/mL (149.5 mM), Sonication is recommended.
Ethanol: 100 mg/mL (299 mM), Sonication is recommended.
溶液配制表
DMSO/DMF/Ethanol
1mg5mg10mg50mg
1 mM2.9900 mL14.9499 mL29.8998 mL149.4992 mL
5 mM0.5980 mL2.9900 mL5.9800 mL29.8998 mL
10 mM0.2990 mL1.4950 mL2.9900 mL14.9499 mL
20 mM0.1495 mL0.7475 mL1.4950 mL7.4750 mL
50 mM0.0598 mL0.2990 mL0.5980 mL2.9900 mL
100 mM0.0299 mL0.1495 mL0.2990 mL1.4950 mL

SCI 文献

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments 一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60% ddH2O. 那么您的工作液浓度为 2 mg/mL 。
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent （ 母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法: 取 50μLDMSOTargetMol | reagent 母液，添加 300 μLPEG300TargetMol | reagent 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
%Tween 80
%ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

Prostaglandin A-2Prostaglandin A2

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