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Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 75-85 KDa and the accession number is Q8R007.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 μg | ¥ 550 | 5日内发货 | |
50 μg | ¥ 1,670 | 5日内发货 | |
500 μg | ¥ 13,700 | 5日内发货 | |
1 mg | ¥ 20,500 | 5日内发货 |
生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
产品描述 | Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 75-85 KDa and the accession number is Q8R007. |
种属 | Mouse |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | Q8R007 |
别名 | Ig superfamily receptor LNIR,PRR4,Nectin-4,PVRL4,LNIR,Poliovirus receptor-related protein 4 |
氨基酸序列 | Gly31-Ile349 |
蛋白构建 | Gly31-Ile349 |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 75-85 KDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. |
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