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UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migration and invasion of this pancreatic cancer cell line.
UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migration and invasion of this pancreatic cancer cell line.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,310 | 35日内发货 | |
5 mg | ¥ 5,910 | 35日内发货 | |
10 mg | ¥ 10,500 | 35日内发货 |
产品描述 | UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migration and invasion of this pancreatic cancer cell line. |
别名 | uPA Inhibitor II, UK122 TFA salt, UK 122 TFA salt, K122 trifloroacetic acid |
分子量 | 405.33 |
分子式 | C19H14F3N3O4 |
CAS No. | 1186653-73-5 |
密度 | 1.31g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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