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EAD1 HCL 是一种有效的自噬 (autophagy) 抑制剂,在肺癌和胰腺癌细胞中具有抗增殖活性。EAD1 HCL 还诱导凋亡 (apoptosis)。
EAD1 HCL 是一种有效的自噬 (autophagy) 抑制剂,在肺癌和胰腺癌细胞中具有抗增殖活性。EAD1 HCL 还诱导凋亡 (apoptosis)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 397 | 现货 | |
2 mg | ¥ 588 | 现货 | |
5 mg | ¥ 1,090 | 现货 | |
10 mg | ¥ 1,630 | 现货 | |
25 mg | ¥ 2,680 | 现货 | |
50 mg | ¥ 3,760 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 1,360 | 现货 |
产品描述 | EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis |
靶点活性 | Autophagy (BxPC3 cells):5.8 μM |
体外活性 | EAD1 HCL (0-200 μM; 72 hours) has antiproliferative activity against human cancer cell lines. EAD1 HCL (5-75 μM; 24 hours) induces apoptosis in the H460 cells in a concentration-dependent manner. EAD1 HCL (1-25 μM; 24 hour) increases the punctate LC3 signal in H460 cells[1]. |
别名 | EAD1 HCL(1644388-26-0 Free base) |
分子量 | 598.45 |
分子式 | C26H28Cl2F3N7O2 |
CAS No. | 2320427-95-8 |
Smiles | [C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COCCCCCCCCCCCCCCCC)OC(C)=O |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 55 mg/mL (105.59 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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