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Azido-PEG8-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Azido-PEG8-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,300 | 2-4周 | |
5 mg | ¥ 3,250 | 2-4周 | |
10 mg | ¥ 4,750 | 2-4周 | |
25 mg | ¥ 7,480 | 2-4周 | |
50 mg | ¥ 9,870 | 2-4周 | |
100 mg | ¥ 13,600 | 2-4周 |
产品描述 | Azido-PEG8-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
别名 | Azido-PEG8-TFP ester |
分子量 | 615.576 |
分子式 | C25H37F4N3O10 |
CAS No. | 1818294-49-3 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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