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TargetMol | Compound Library

抗心血管疾病化合物库现货

Anti-Cardiovascular Disease Compound Library

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产品编号 L5400

心血管疾病泛指由于动脉粥样硬化、高脂血症、血液黏稠、高血压等所导致的心脏、大脑及全身组织发生的缺血性或出血性疾病,例如心绞痛、心肌梗塞、中风等,是全球死亡的首要原因。不同类型疾病的发病机制不同,各种抗氧化、抗高血脂、抗缺血、抑制血小板聚集和抗炎物质都具有降低心血管疾病风险的作用。某些天然产物具有抑制粘附分子、细胞因子和趋化因子基因表达,抑制血小板功能,增强内皮细胞一氧化氮释放,抑制平滑肌活化的作用,这些化合物都是心血管疾病药物筛选中的重要工具。 TargetMol 抗心血管疾病化合物库是由 1793 个心血管疾病相关的化合物组成的综合筛选库,用于心血管疾病的相关研究和高通量高内涵筛选。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L5400

抗心血管疾病化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 1793种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
  • 靶点包括膜转运体、离子通道等心血管疾病相关靶点;
  • 大部分产品是经FDA、EMA或NMPA批准上市的药物,是研究心血管相关疾病的有效工具;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

Adrenergic Receptor
Calcium Channel
PDE
Apoptosis
Autophagy
VEGFR
COX
Sodium Channel
Endogenous Metabolite
Potassium Channel
AChR
5-HT Receptor
RAAS
Antibacterial
Dopamine Receptor
TNF
PDGFR
NF-κB
IL Receptor
Histone Acetyltransferase
FGFR
Histamine Receptor
PARP
FLT
JAK
c-Kit
PPAR
CDK
Parasite
HMG-CoA Reductase
Factor Xa
Antioxidant
BACE
PKC
Reactive Oxygen Species
EGFR
Epigenetic Reader Domain
P450
Carbonic Anhydrase
Antifungal
Adenosine Receptor
IGF-1R
ATPase
Antibiotic
Src
Thrombin
p38 MAPK
c-Met/HGFR
Influenza Virus
Mitophagy
TRP/TRPV Channel
Norepinephrine
Ferroptosis
Phospholipase
c-RET
ERK
Glucocorticoid Receptor
Lipoxygenase
Beta-Secretase
HIV Protease
PI3K
P2Y Receptor
Drug Metabolite
Akt
DNA/RNA Synthesis
PKA
ROS
P-gp
Beta Amyloid
NO Synthase
HER
MRP
Guanylate cyclase
CaMK
Prostaglandin Receptor
Nrf2
STAT
GABA Receptor
Proteasome
GSK-3
Serine/threonin kinase
iGluR
Bcr-Abl
Raf
NMDAR
Aurora Kinase
Interleukin
SARS-CoV
Acetyl-CoA Carboxylase
HDAC
Anti-infection
Proton pump
Integrin
Dehydrogenase
CETP
Virus Protease
Serotonin Transporter
ROCK
Topoisomerase
Mitochondrial Metabolism
Angiotensin-converting Enzyme (ACE)
Acyltransferase
c-Fms
Hydroxylase
MEK
NOD
Tyrosine Kinases
Serine Protease
Liver X Receptor
Caspase
MAO
P2X Receptor
Epoxide Hydrolase
GluR
Trk receptor
IκB/IKK
AMPK
Tyrosinase
HIF/HIF Prolyl-Hydroxylase
Chloride channel
NOS
NADPH
Tie-2
Glutathione Peroxidase
Wnt/beta-catenin
Nucleoside Antimetabolite/Analog
LDL
Opioid Receptor
DPP-4
HSV
Chk
cAMP
mTOR
PGE Synthase
AChE
Ephrin Receptor
HIF
Sigma receptor
TAM Receptor
Protease-activated Receptor
NOD-like Receptor (NLR)
Imidazoline Receptor
p53
Monoamine Oxidase
Thyroid hormone receptor(THR)
Estrogen/progestogen Receptor
Arginase
DNA Alkylator/Crosslinker
JNK
Antifolate
FXR
CSF-1R
Myosin
Na-K-Cl cotransporter
BCL
HCN Channel
Fatty Acid Synthase
Endothelin Receptor
TLR
transporter
RSV
Neprilysin
Reverse Transcriptase
PDK
Platelet aggregation
Syk
NADPH-oxidase
S6 Kinase
Microtubule Associated
FAK
Adenylyl cyclase
Transferase
DHFR
Histone Methyltransferase
ADC Cytotoxin
Amino Acids and Derivatives
Sodium-dependent phosphate transporter
LTR
Na+/Ca2+ Exchanger
Histone Demethylase
ABC
HBV
Estrogen Receptor/ERR
Rho
Leukotriene Receptor
PYK2
Vitamin
Amylase
Immunology/Inflammation related
UGT
PAFR
Antifection
Monoamine Transporter
DNA Alkylation
FAAH
Xanthine Oxidase
DNA
Androgen Receptor
TGF-beta/Smad
MAPK
Antiviral
Aminopeptidase
Sirtuin
PAI-1
ALK
GST
GPR
SGK
DNA Methyltransferase
AhR
NPC1L1
Monocarboxylate transporter
ROR
DNA-PK
HCV Protease
DprE1
YAP
Reductase
IFNAR
Lipase
PERK
Phosphatase
Progesterone Receptor
N-Acetylglucosaminyltransferase
VDAC
Pim
cell cycle arrest
Cysteine Protease
Neurotensin Receptor
Glucokinase
NAMPT
Aryl Hydrocarbon Receptor
IAP
IRE1
Annexin A
FLAP
RIP kinase
Adiponectin receptor
GRK
DNA gyrase
GlyT
Glucosidase
BTK
Anion Exchanger
Isocitrate Dehydrogenase (IDH)
CCR
Vasopressin Receptor
MMP
ACK
Thrombopoietin Receptor
Indoleamine 2,3-Dioxygenase (IDO)
ATP Citrate Lyase
Lipid
BCRP
OAT
HSP
Decarboxylase
ASK
Casein Kinase
Retinoid Receptor
Aromatase
CRISPR/Cas9
RXFP receptor
PLK
Cannabinoid Receptor
Gap Junction Protein
DAPK
Discoidin Domain Receptor (DDR)
IRAK
Ras
p97
CFTR
MLK
PKM
S1P Receptor

Keywords