Mal-amido-PEG12-acid

Name: Mal-amido-PEG12-acid
Brand: TargetMol
SKU: T18236
Price: 2320 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T18236Cas号 2378428-27-2

Mal-amido-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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Mal-amido-PEG12-acid

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产品编号 T18236Cas号 2378428-27-2

规格	价格	库存
5 mg	¥ 245	2-4周
10 mg	¥ 347	2-4周
25 mg	¥ 565	2-4周
50 mg	¥ 828	2-4周
100 mg	¥ 1,320	2-4周

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产品介绍

生物活性

产品描述	Mal-amido-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
体外活性	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].