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TargetMol | Compound Library

干细胞分化化合物库现货

Stem Cell Differentiation Compound Library
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货号 L8000

干细胞具有分化成特定细胞亚型的能力,例如,胚胎干细胞可以产生所有三个胚层的细胞:外胚层、中胚层和内胚层。通常认为成体干细胞效力有限,只能分化成某些细胞类型。为了产生用于再生医学、药物筛选、疾病或发育模型相关的特化细胞类型,研究人员必须控制和指导干细胞的分化。细胞的分化方向可以通过天然或化学合成的小分子来诱导。例如,糖原合成酶激酶-3β的特异性抑制剂可以诱导多能干细胞中的神经元分化,特定细胞因子和组蛋白去乙酰化酶抑制剂丁酸钠的组合诱导干细胞分化成肝细胞等。

TargetMol 干细胞分化化合物库是1880 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,为干细胞相关研究提供有效工具。

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货号 L8000

干细胞分化化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 1880种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;
  • 研究干细胞再生机理、再生疗法;是用于干细胞分化信号通路的研究以及基于干细胞的新药物筛选的有效工具;
  • 靶点含Wnt、GSK-3、Hedgehog、JAK、ROCK、γ-secretase等;
  • 结构多样,药效显著,可渗透细胞;
  • 详细的说明书、化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

包装和储存 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。
  • 本化合物库通常以 DMSO 10 mM 浓度提供。少量产品可能因溶解性或稳定性需求,采用其他溶剂或浓度包装,具体以实际产品信息为准。

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Apoptosis
Autophagy
EGFR
Wnt/beta-catenin
STAT
JAK
PI3K
Ras
Akt
GSK-3
TGF-beta/Smad
NF-κB
p38 MAPK
mTOR
ERK
Antibacterial
CDK
Endogenous Metabolite
Casein Kinase
PPAR
ROCK
Gamma-secretase
Histone Methyltransferase
ROS
ALK
AMPK
Hedgehog/Smoothened
Kras
Interleukin
Potassium Channel
Src
PKC
VEGFR
Tyrosine Kinases
Caspase
COX
FLT
Parasite
YAP
JNK
Antibiotic
Smo
MDM-2/p53
TNF
PKA
IGF-1R
S6 Kinase
PARP
HER
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Raf
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Bcl-2 Family
DNA-PK
MAPK
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FGFR
MEK
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Epigenetic Reader Domain
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Rho
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IL Receptor
PDE
Nrf2
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c-Met/HGFR
MMP
HIF/HIF Prolyl-Hydroxylase
Dehydrogenase
DNA Methyltransferase
IκB/IKK
AChR
Histone Acetyltransferase
Sirtuin
Phosphatase
CXCR
E1/E2/E3 Enzyme
TLR
Adrenergic Receptor
HSV
Porcupine
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Mdm2
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c-Myc
Lipoxygenase
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FAK
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Hippo pathway
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Topoisomerase
MLK
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IKZF
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Thrombopoietin Receptor
Androgen Receptor
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Protease-activated Receptor
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