LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc)

产品编号 TMPK-00682

LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 75.2 kDa and the accession number is NP_001035762.2.

LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc)

产品编号 TMPK-00682

规格	价格	库存
100 μg	¥ 2,960	5日内发货
500 μg	¥ 11,800	5日内发货
1 mg	¥ 19,700	5日内发货

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产品信息

生物活性	Rhesus macaque LILRB1, hFc Tag captured on CM5 Chip via Protein A can bind Rhesus macaque HLA-G Complex Tetramer, His Tag with an affinity constant of 1.74 nM as determined in SPR assay.
产品描述	LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 75.2 kDa and the accession number is NP_001035762.2.
种属	Rhesus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	NP_001035762.2
别名	XXbac-BCX85G21.4,MIR7,LIR1,LILRB1,ILT2FLJ37515,ILT-2,ILT2,CD85J
蛋白构建	Met1-His474
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	75.2 kDa (predicted). Due to glycosylation, the protein migrates to 80-90 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.