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Sabialimon P (compound 16) 具抗炎功效,为一种有效的NO释放抑制剂(IC50=18.12 μM)。它可以显著抑制LPS诱导RAW264.7细胞中TNF-α、iNOS、IL-6及NF-κB的产生,并减少COX-2与NF-κB/p65的表达。
Sabialimon P (compound 16) 具抗炎功效,为一种有效的NO释放抑制剂(IC50=18.12 μM)。它可以显著抑制LPS诱导RAW264.7细胞中TNF-α、iNOS、IL-6及NF-κB的产生,并减少COX-2与NF-κB/p65的表达。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release inhibitor and exhibits anti-inflammatory properties. It effectively diminishes the secretion of TNF-α, iNOS, IL-6, and NF-κB, and suppresses the expression of COX-2 and NF-κB/p65 in LPS-induced RAW264.7 cells. |
分子量 | 486.73 |
分子式 | C31H50O4 |
CAS No. | 2267333-96-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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