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B 细胞 CD 蛋白 (B Cell CD Proteins)

B细胞,也称为B淋巴细胞,是淋巴细胞亚型的一种白细胞。它们在适应性免疫系统的体液免疫成分中起作用。在哺乳动物中,B细胞在骨髓中成熟。B 细胞活化发生在次级淋巴器官 (SLO) 中,例如脾脏和淋巴结。B细胞在骨髓中成熟后,它们通过血液迁移到SLO,SLO通过循环淋巴液获得持续的抗原供应。在 SLO 中,当 B 细胞通过其 BCR 与抗原结合时,B 细胞激活开始。 未成熟的 B 细胞可表达 CD19、CD20、CD34、CD38 和 CD45R。大多数成熟 B 细胞表达IgM、CD19、CD20 和 CD22。活化的 B 细胞会表达 CD30。血浆 B 细胞不能表达 CD19,但可表达 CD78。

  • TLR4 Protein, Human, Recombinant (His)
    TMPY-02904
    TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. TLR 4 has also been designated as CD284 (cluster of differentiation 284). It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. TLR4 Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It is also involved in LPS-independent inflammatory responses triggered by Ni(2+).
    • ¥ 3820
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  • BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
    TMPK-00176
    B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B TACI, TNFRSF17 BCMA, and TNFRSF13C BAFF-R. BAFF TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 52.4 kDa and the accession number is Q9Y275-1.
    • ¥ 3250
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  • CD19 Protein, Mouse, Recombinant (His), Biotinylated
    TMPY-05540
    CD19 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P25918.
    • ¥ 3130
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  • BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
    TMPJ-01391
    BAFF TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the accession number is Q9WU72.
    • ¥ 550
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  • SDC1 Protein, Human, Recombinant (His)
    TMPJ-00488
    SDC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 45-60 KDa and the accession number is AAH08765.1.
    • ¥ 1170
    5日内发货
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  • CD74 Protein, Human, Recombinant (His)
    TMPY-01199
    CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
    • ¥ 3690
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  • CD93/C1qR1 Protein, Mouse, Recombinant (hFc)
    TMPY-06844
    CD93 C1qR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.83 kDa and the accession number is NP_034870.1.
    • ¥ 3820
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  • CD19 Protein, Human, Recombinant (His), Biotinylated
    TMPY-05127
    CD19 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391.
    • ¥ 2440
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  • BAFF/TNFSF13B Protein, Human, Recombinant (His)
    TMPJ-00178
    BAFF TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accession number is Q9Y275.
    • ¥ 850
    5日内发货
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  • CD28 Protein, Human/Cynomolgus, Recombinant (His)
    TMPJ-00103
    CD28 Protein, Human Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is P10747.
    • ¥ 550
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  • ILDR2 Protein, Human, Recombinant (His)
    TMPJ-00353
    ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic cells (DC2 cells, a subpopulation of polarized DCs that promotes Th2 differentiation). Recent publications reported that ILDR2 displayed negative regulatory functions on human and mouse T cells in various experimental systems. Fusion protein of ILDR2 lumenal domain with an Fc fragment, displays therapeutic effects in collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA). ILDR2 represents a novel B7-like ligand that exerts negative immune modulation via interaction with a putative counterpart receptor expressed on activated T cells.
    • ¥ 550
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  • SLAMF5 Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPJ-00228
    SLAMF5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 40-50 KDa and the accession number is Q9UIB8.
    • ¥ 2260
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  • CD28 Protein, Mouse, Recombinant (hFc & His)
    TMPJ-00099
    T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
    • ¥ 220
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  • CD19 Protein, Rhesus macaque, Recombinant (hFc)
    TMPJ-00329
    CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
    • ¥ 1170
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  • CD40 Protein, Cynomolgus, Recombinant (His)
    TMPJ-00634
    CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
    • ¥ 740
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  • SLAMF5 Protein, Mouse, Recombinant (His)
    TMPJ-00455
    CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. CD84 expression has been documented on several hematopoietic cell types, including monocytes, macrophages, dendritic cells, B lymphocytes, and platelets. Activation of cell surface CD84 initiates a signaling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation, which in turn enhances cell survival. Either immunoneutralization or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.
    • ¥ 740
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  • BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)
    TMPJ-01446
    BCMA TNFRSF17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 12 and 15-20 KDa and the accession number is G7Q0I4.
    • ¥ 550
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  • CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated
    TMPK-00111
    CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human Cynomolgus Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is P10747.
    • ¥ 5180
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  • CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated
    TMPK-00006
    CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.5 kDa and the accession number is P25063-1.
    • ¥ 5180
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  • CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
    TMPK-00300
    CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.9 kDa and the accession number is P13379.
    • ¥ 5180
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  • Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00593
    Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 kDa and the accession number is AAH08765.
    • ¥ 5180
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  • Syndecan-1 Protein, Rabbit, Recombinant (His)
    TMPK-01310
    CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.
    • ¥ 3700
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  • CD28 Protein, Canine, Recombinant (His)
    TMPK-01176
    CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 16.7 kDa and the accession number is Q9GKP3.
    • ¥ 2960
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  • BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi)
    TMPK-00071
    B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA TNFRSF17 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.5 kDa and the accession number is O88472-1.
    • ¥ 3400
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  • IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)
    TMPK-00164
    Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. IL-2 R alpha CD25 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.6 kDa and the accession number is P01589.
    • ¥ 2960
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  • CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated
    TMPK-00302
    CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127.
    • ¥ 5180
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  • CD20 Protein-VLP, Canine, Recombinant (His)
    TMPH-00483
    CD20 Protein-VLP, Canine, Recombinant (His) is expressed in HEK293.
    • ¥ 3370
    20日内发货
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  • CD44 Protein, Human, Recombinant (His & SUMO)
    TMPH-01071
    CD44 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 80.2 kDa and the accession number is P16070.
    • ¥ 1320
    20日内发货
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  • BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)
    TMPY-01211
    BCMA TNFRSF17 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 33.7 kDa and the accession number is O88472-1.
    • ¥ 3820
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  • Fas/CD95 Protein, Mouse, Recombinant (His)
    TMPY-01426
    Fas CD95 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is P25446.
    • ¥ 3820
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  • CD27/TNFRSF7 Protein, Mouse, Recombinant (His & hFc)
    TMPY-01378
    CD27 TNFRSF7 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is P41272.
    • ¥ 4460
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  • CD10 Protein, Human, Recombinant (hFc)
    TMPY-00759
    CD10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 106 kDa and the accession number is P08473.
    • ¥ 3170
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  • IL-7R alpha/CD127 Protein, Human, Recombinant (His)
    TMPY-01209
    IL-7R alpha CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
    • ¥ 4470
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  • Syndecan-1 Protein, Human, Recombinant (His)
    TMPY-01630
    Syndecan-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P18827.
    • ¥ 3820
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  • CD27/TNFRSF7 Protein, Mouse, Recombinant (His)
    TMPY-01432
    CD27 TNFRSF7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is P41272.
    • ¥ 4460
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  • Fas/CD95 Protein, Rat, Recombinant (His)
    TMPY-02057
    Fas CD95 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is A6I127.
    • ¥ 3820
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  • Fas/CD95 Protein, Human, Recombinant (His)
    TMPY-01704
    Fas CD95 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is P25445-1.
    • ¥ 3820
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  • CD34 Protein, Mouse, Recombinant (His)
    TMPY-01652
    CD34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q543Y2.
    • ¥ 3820
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  • CD79B Protein, Mouse, Recombinant (His)
    TMPY-02265
    CD79B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is P15530.
    • ¥ 3820
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  • CD20 Protein, Ferret, Recombinant (His)
    TMPY-02218
    CD20 Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa.
    • ¥ 3820
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  • CD24 Protein, Mouse, Recombinant (hFc)
    TMPY-03016
    CD24 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 29.7 kDa and the accession number is P24807.
    • ¥ 3130
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  • ITGB1 Protein, Pig, Recombinant (His & Myc)
    TMPH-03114
    ITGB1 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.1 kDa and the accession number is Q9GLP0.
    • ¥ 2290
    20日内发货
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  • CD40 Protein, Canine, Recombinant (His)
    TMPY-04089
    CD40 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q7YRL5.
    • ¥ 3820
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  • Siglec-2/CD22 Protein, Mouse, Recombinant (His)
    TMPY-04083
    Siglec-2 CD22 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.8 kDa and the accession number is Q3U0M3.
    • ¥ 3820
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  • CD45 Protein, Mouse, Recombinant (hFc)
    TMPY-04277
    CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
    • ¥ 3820
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  • CD28 Protein, Rat, Recombinant (His)
    TMPY-04252
    CD28 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is A6IPD4.
    • ¥ 5100
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  • BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
    TMPY-05197
    BCMA TNFRSF17 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is Q02223-1.
    • ¥ 3820
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  • CD69 Protein, Mouse, Recombinant (His)
    TMPY-04232
    CD69 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is P37217.
    • ¥ 4460
    5日内发货
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