按潜在通路靶点分类

ChemDiv开发了RNA等位三核苷酸模拟物库，该化合物库包含29000个小分子化合物，专门用于靶向RNA 扩展重复序列。

Life Chemicals has developed its RNA Screening Library of over 4,400 drug-like compounds with predicted RNA-binding activity as an excellent starting point for post-transcriptional gene regulation, antibacterial, and antiviral drug discovery research.

ChemDiv’s RNA-Protein Interaction Inhibitors Library contains 2,111 compounds.

Life Chemicals has designed a library of potential GPCR modulators based on known structure and activity data for GPCR targeting compounds available publicly.

Cysteine Protease Focused Library comprises over 3,700 screening compounds with potential inhibitory activity against cysteine proteases.

Over 2,500 screening compounds of potential helicase inhibitors were selected, with the most active compounds placed at the top of the list.

ATP酶靶向库，其中包含超过13,500个类似药物的筛选化合物。

Life Chemicals has designed a novel Screening Library of GPCR targeting compounds intended for screening in GPCR-related drug discovery projects.

含2.1万种潜在活性小分子化合物，是表观转录组学、免疫系统和中枢神经系统疾病相关研究的有力工具。

Life Chemicals has designed a new Tyrosine Kinase Screening Library of about 5,700 drug-like screening compounds offered for high throughput screening (HTS).

Serine proteases are one of the most biologically important families of proteins that have been shown to play multifarious roles in various diseases (such as cancer proliferation, auto-immune disorders, and allergy).

Over 17,000 structurally diverse molecules with potential polymerase inhibition activity.

The Matrix Metalloproteinase Focused Library contains over 2,000 screening compounds.

Life Chemicals offers its new Chelator Library (over 5,700 compounds) that is based on a variety of metal-binding groups.

OTAVAchemicals offers Transporter Modulators Library (525 compounds).

利用我们在合成trans-十氢萘相关的多氧骨架方面的努力，我们开发了一个非含氮化合物库，用于筛选传统上需要碱性化合物的GPCR靶点。

ChemDiv’s PTPs-targeted library contains 15,000 compounds and design at CDL involves:

OTAVAchemicals offers a high-quality PDZ Domain Targeted Library.

激酶ATP位点结合剂筛选库包含24000个化合物，旨在发现新型激酶ATP 口袋结合物。

We offer SARS-CoV-2 Endoribonuclease (NSP15) Targeted Library, which contains 626 compounds.

OTAVAchemicals 11β-HSD1 Targeted Library (924 compounds) has been designed with flexible molecular docking.

ChemDiv’s Proline Kinase Library contains 2,000 compounds.

ChemDiv’s Autophagy-Targeted Library contains 4,550 compounds.

OTAVAchemicals offers Enhancer of Zeste Homolog 2 (EZH2) Targeted Library. It contains 979 compounds with predicted inhibitory activity against this enzyme.

iPPI Bayesian Library with 2637 compounds was prepared using Bayesian modeling (ECFP6 and FCFP6 fingerprints) based on known active PPI inhibitors (IC50<100 nM) taken from the TIMBAL database.

OTAVAchemicals offers SARS-CoV-2 RNA-dependent RNA Polymerase (RdRp) Targeted Library, which contains 1031 compounds with predicted activity against SARS-CoV-2 RdRp.

ChemDiv’s Antimitotic Tubulin Library contains 18,000 compounds.

Mitogen-activated protein kinase 1 (MAPK1 ERK2) inhibitor library contains 197 compounds.

ChemDiv designed a novel library of 5000 compounds

We have designed an MDM2-targeted library of more than 23K small molecule compounds.

ChemDiv’s Protein Kinases Inhibitors Library contains 38,000 compounds.

Estrogen receptor β (ERβ) antagonist library in Otava contains 464 compounds.

ChemDiv’s Bcl2-PPI Inhibitors Library contains 11,000 compounds.

GPCR agonist general library in Otava contains 465 compounds

ChemDiv’s Type ll Kinase Inhibitors Library contains 8,000 compounds.

Beta-adrenergic receptor kinase (BARK) inhibitor library in Otava contains 1268 compounds

Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Blocker library (657 compounds in total) was designed as a special screening library containing compounds with predicted HCN channels blocking activity and selectivity.

The ChemDiv library contains 27,000 compounds targeted at Macl-GPIb alpha Interaction.

Estrogen receptor β (ERβ) agonist library in Otava contains 416 compounds.