Life Chemicals has developed its RNA Screening Library of over 4,400 drug-like compounds with predicted RNA-binding activity as an excellent starting point for post-transcriptional gene regulation, antibacterial, and antiviral drug discovery research.
Life Chemicals has designed a library of potential GPCR modulators based on known structure and activity data for GPCR targeting compounds available publicly.
Life Chemicals has designed a new Tyrosine Kinase Screening Library of about 5,700 drug-like screening compounds offered for high throughput screening (HTS).
Serine proteases are one of the most biologically important families of proteins that have been shown to play multifarious roles in various diseases (such as cancer proliferation, auto-immune disorders, and allergy).
OTAVAchemicals offers Enhancer of Zeste Homolog 2 (EZH2) Targeted Library. It contains 979 compounds with predicted inhibitory activity against this enzyme.
iPPI Bayesian Library with 2637 compounds was prepared using Bayesian modeling (ECFP6 and FCFP6 fingerprints) based on known active PPI inhibitors (IC50<100 nM) taken from the TIMBAL database.
The Life Chemicals Receptor-based Screening Library contains over 2,000 potential lysine-specific demethylase 4A (KDM4A) inhibitors selected with computational chemistry and virtual screening techniques. The Library presented is a rich source of inhibitors for screening projects in KDM-related drug discovery.
Life Chemicals has designed a Library of over 3,900 drug-like screening compounds that are small-molecule analogs of known ligase inhibitors with experimentally determined activity.