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CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy.
CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 560 | 35日内发货 | |
5 mg | ¥ 2,430 | 35日内发货 | |
10 mg | ¥ 4,250 | 35日内发货 | |
25 mg | ¥ 9,320 | 35日内发货 |
产品描述 | CAY10721 is an inhibitor of sirtuin 3 (SIRT3), a class III HDAC (39% SIRT3 inhibition at 200 μM). Upregulation of SIRT3 transcription is associated with oral squamous cell carcinoma (OSCC) and breast cancer with lymph node involvement, while SIRT3 down-regulation inhibits the growth of OSCC cells and sensitizes them to radiation and chemotherapy. |
分子量 | 351.38 |
分子式 | C18H13N3O3S |
CAS No. | 848688-62-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | DMSO: 30 mg/mL DMF: 30 mg/mL DMSO:PBS(pH 7.2) (1:4): 0.20 mg/mL |
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