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CD40 Ligand Trimer Protein, Human, Recombinant (hFc)

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货号 TMPK-01398

别名 TRAP, TNFSF5IMD3, TNFSF5, T-BAM, IMD3, IGM, HIGM1, gp39, CD40LIGM, CD40LG, CD40L, CD40 Ligand, CD154

CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
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CD40 Ligand Trimer Protein, Human, Recombinant (hFc)

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SPR兼容缓冲液
货号 TMPK-01398 别名 TRAP, TNFSF5IMD3, TNFSF5, T-BAM, IMD3, IGM, HIGM1, gp39, CD40LIGM, CD40LG, CD40L, CD40 Ligand, CD154

CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

规格价格库存数量
5 μg
¥ 313
6-8日内发货
10 μg
¥ 498
6-8日内发货
20 μg
¥ 812
5日内发货
50 μg
¥ 1,580
5日内发货
100 μg
¥ 2,660
5日内发货
200 μg
¥ 4,830
5日内发货
500 μg
¥ 10,600
5日内发货
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产品介绍

生物活性
产品描述
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
生物活性
1. Immobilized Human CD40, His Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Human CD40 Ligand (Trimer) , hFc Tag with the EC50 of 9.0 ng/ml determined by ELISA (QC Test).
_x000D_ 2. Serial dilutions of Anti-CD40 Antibody were added into Biotinylated Human CD40, His Tag : Human CD40 Ligand (Trimer) , hFc Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 2.0 μg/ml.
研究背景
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
种属
Human
表达系统
HEK293 Cells
标签N-hFc
蛋白编号P29965
蛋白构建Met113-Leu261
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名TRAP, TNFSF5IMD3, TNFSF5, T-BAM, IMD3, IGM, HIGM1, gp39, CD40LIGM, CD40LG, CD40L, CD40 Ligand, CD154
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量74.9 kDa (predicted). Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
密度no data available
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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关键词

CD40LigandTrimerProtein,Human,Recombinant(hFc)
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