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TargetMol | Compound Library

抗癌药物库现货

Anti-Cancer Drug Library

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产品编号 L2150

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力；并且表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。 我们挑选了3230 种具有抗癌活性或潜在抗癌活性的药物，包括上市和临床期药物，可用于具体癌症的阳性对照及不同癌症之间相关性研究，是您抗癌研究的有力工具！

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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产品编号 L2150

抗癌药物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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产品描述 产品描述

  • 3230个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；
  • 所有化合物都具有已知且良好的生物活性、安全性和生物利用度，这些特性可显著加速药物开发和优化，是进行癌症相关研究和药物重定位有效的筛选工具；
  • 作用靶点涉及PI3K、HDAC、mTOR、CDK、JAK 等癌症相关靶点，涉及的研究领域包括肺癌、乳腺癌、白血病、淋巴瘤等15种癌症；
  • 结构多样，药效显著，可渗透细胞；
  • 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
  • 干粉蓝冰运输，DMSO溶液干冰运输；
  • 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。

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Supporting Files | TargetMol 文件下载

化合物库操作手册 (635 KB) Targetmol化合物库目录 (60.2 MB)

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Autophagy
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5-HT Receptor
Endogenous Metabolite
Adrenergic Receptor
Antibacterial
COX
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Histamine Receptor
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Antibiotic
Sodium Channel
VEGFR
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Parasite
PI3K
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Reactive Oxygen Species
Cytochromes P450
CDK
Topoisomerase
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HIV Protease
NF-κB
PDGFR
PPAR
GABA Receptor
JAK
c-Kit
HDAC
FGFR
Estrogen/progestogen Receptor
Microtubule Associated
c-Met/HGFR
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Src
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ATPase
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HSP
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ALK
TNF
PKC
BTK
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Epigenetic Reader Domain
MEK
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NMDAR
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DNA Alkylator/Crosslinker
RAAS
ROS
Phosphatase
ERK
c-RET
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HBV
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Trk receptor
Bcl-2 Family
AMPK
HCV Protease
GSK-3
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MMP
Carbonic Anhydrase
Progesterone Receptor
Caspase
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GPCR19
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ribosome
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LTR
Melatonin Receptor
CaSR
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MT Receptor
Na-K-Cl cotransporter
Hexokinase
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transporter
Decarboxylase
GST
Oxytocin Receptor
Adenosine Deaminase
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NOD-like Receptor (NLR)
NEDD8
Ligands for Target Protein for PROTAC
Arginase
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VDA
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Vitamin
IRE1
LDL
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HCN Channel
Telomerase
ATP Citrate Lyase
BCRP
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Porcupine
CD73
LPA Receptor
Gap Junction Protein
Discoidin Domain Receptor (DDR)
p97
MLK
Imidazoline Receptor
Advanced Glycation End Products
NPC1L1
Hydrogenase
MALT
Na+/Ca2+ Exchanger
BACE
DYRK
RAR/RXR 
Lipase
gp120/CD4
TOPK
GTPase
Factor Xa
Galectin
N-Acetylglucosaminyltransferase
Hck
Neurotensin Receptor
Glucokinase
Stemness kinase
Immunology/Inflammation related
Myosin
Adiponectin Receptor
PAFR
MTH1
GRK
GlyT
Anion Exchanger
PROTAC Linker
Thioredoxin
FAAH
ACK1
PAD
cAMP
Thrombopoietin Receptor
Lipid
Glutathione reductase
MNK
Survivin
Histone Acetyltransferase
ASK
GluCls
PAI-1
Pyroptosis
MELK
Methionine Adenosyltransferase (MAT)
Hippo pathway
Neprilysin
PI4K
KLF
Aquaporin
RXFP receptor
SGK
Complement System
Platelet aggregation
NADPH-oxidase
BMI-1

Keywords

AntiCancer Drug LibraryAnti Cancer Drug Library
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