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DMH-25 是一种新型共价有效的 mTOR 抑制剂,在体内对三阴性乳腺癌细胞具有抗肿瘤活性。
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DMH-25 是一种新型共价有效的 mTOR 抑制剂,在体内对三阴性乳腺癌细胞具有抗肿瘤活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 773 | 现货 | |
5 mg | ¥ 1,750 | 现货 | |
10 mg | ¥ 2,590 | 现货 | |
25 mg | ¥ 4,130 | 现货 | |
50 mg | ¥ 5,590 | 现货 | |
100 mg | ¥ 7,500 | 现货 | |
200 mg | ¥ 9,870 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 2,050 | 现货 |
产品描述 | DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells. |
体内活性 | In vivo, DHM25 was an efficient inhibitor of growth and metastasis of triple-negative breast cancer cells, paving the way for its clinical application in oncology. Constitutive activation of the PI3K/mTOR signaling pathway contributes to carcinogenesis and metastasis in most, if not all, breast cancers. |
分子量 | 489.94 |
分子式 | C15H8Br3NO3 |
CAS No. | 1685280-21-0 |
Smiles | N(=O)(=O)C=1C(OC=2C(C1)=CC(Br)=CC2Br)C3=CC=C(Br)C=C3 |
密度 | 2.12 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 25 mg/mL (51.03 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
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