购物车
- 全部删除
您的购物车当前为空
15(R)-Lipoxin A4
还可以产品编号 T37265Cas号 171030-11-8
别名 AT-Lipoxin A4, 15(R)-Lipoxin A4
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may be ascribed in part to the ability of 15(R)-LXA4 to regulate leukocyte function.[4] 15(R)-LXA4 is reported to promote resolution of inflammation in LPS-treated stromal cells derived from intermediate-stage diseased supraspinatus tendons as evidenced by increased expression of the STAT-6 pathway target genes, ALOX15 and CD206.[5]
15(R)-Lipoxin A4
还可以产品编号 T37265 别名 AT-Lipoxin A4, 15(R)-Lipoxin A4Cas号 171030-11-8
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may be ascribed in part to the ability of 15(R)-LXA4 to regulate leukocyte function.[4] 15(R)-LXA4 is reported to promote resolution of inflammation in LPS-treated stromal cells derived from intermediate-stage diseased supraspinatus tendons as evidenced by increased expression of the STAT-6 pathway target genes, ALOX15 and CD206.[5]
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 3,510 | 35日内发货 | |
| 50 μg | ¥ 6,680 | 35日内发货 | |
| 100 μg | ¥ 12,600 | 35日内发货 | |
| 250 μg | ¥ 28,000 | 35日内发货 |
大包装 & 定制
加入购物车
实验操作小课堂
查看更多 联系我们获取更多批次信息
资源下载
产品介绍
生物活性
化学信息
| 产品描述 | Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may be ascribed in part to the ability of 15(R)-LXA4 to regulate leukocyte function.[4] 15(R)-LXA4 is reported to promote resolution of inflammation in LPS-treated stromal cells derived from intermediate-stage diseased supraspinatus tendons as evidenced by increased expression of the STAT-6 pathway target genes, ALOX15 and CD206.[5] |
| 别名 | AT-Lipoxin A4, 15(R)-Lipoxin A4 |
| 分子量 | 352.47 |
| 分子式 | C20H32O5 |
| CAS No. | 171030-11-8 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | DMF: 50 mg/mL Ethanol: 50 mg/mL PBS (pH 7.2): 1 mg/mL |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
评论列表
预览
Related Tags: buy 15(R)-Lipoxin A4 | purchase 15(R)-Lipoxin A4 | 15(R)-Lipoxin A4 cost | order 15(R)-Lipoxin A4 | 15(R)-Lipoxin A4 chemical structure | 15(R)-Lipoxin A4 formula | 15(R)-Lipoxin A4 molecular weight
嗨！很高兴为您提供帮助！
评论内容