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IL-20RB Protein, Rat, Recombinant (hFc)

产品编号 TMPY-03086

别名: interleukin 20 receptor beta, interleukin 20 receptor β

IL-20RB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.2 kDa and the accession number is B8K1X9.

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IL-20RB Protein, Rat, Recombinant (hFc)

规格	价格/CNY		货期	数量
100 μg	￥ 3,820		5日内发货

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生物活性	Testing in progress
产品描述	IL-20RB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.2 kDa and the accession number is B8K1X9.

种属	Rat
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	B8K1X9
别名	interleukin 20 receptor beta, interleukin 20 receptor β
蛋白构建	The Rat IL20RB (B8K1X9) (Met1-Pro227) was expressed, fused with the Fc region of Human IgG1 at the C-terminus.
蛋白纯度	> 70 % as determined by SDS-PAGE
分子量	50.2 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20, and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA form a heterodimeric receptor for interleukin-20.

参考文献

1. Zhu H,et al.(2009) Expression pattern of mda-7/IL-24 receptors in liver cancer cell lines. Hepatobiliary Pancreat Dis Int. 8(4):402-6. 2. Logsdon NJ,et al.(2012) Purification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 68(Pt 1):89-92. 3. Kingo K,et al.(2008) Association analysis of IL20RA and IL20RB genes in psoriasis. Genes Immun. 9(5):445-51.

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Keywords

IL-20RB Protein, Rat, Recombinant (hFc) interleukin 20 receptor beta interleukin 20 receptor β recombinant recombinant-proteins proteins protein

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