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Adiponectin receptor

Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ADIPOR1 gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR1.The adiponectin receptors, AdipoR1 and AdipoR2, serve as receptors for globular and full-length adiponectin and mediate increased AMPK and PPAR-α ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.

AdipoRon
T2257924416-43-3
AdipoRon (SC-396658) 是可口服的脂联素受体激动剂,能够与AdipoR1(Kd:1.8 μM)及AdipoR2(Kd:3.1 μM)结合。
  • ¥ 265
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Ticlopidine
T419055142-85-3
Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂,抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂,能够阻断 NTPDase 同工酶,对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
  • ¥ 235
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Arctiin
T276620362-31-6
Arctiin (Arctigenin-4-glucoside) 是一种从牛蒡种子中提取的植物木酚素,具有抗癌作用。
  • ¥ 133
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Zeaxanthin dipalmitate
TN4773144-67-2
Zeaxanthin dipalmitate (Physalien) 是一种存在于水果中的叶黄素类胡萝卜素,具有抗炎活性、保肝活性和抗氧化应激作用,可减轻乙醇诱导的肝损伤。Zeaxanthin dipalmitate 恢复乙醇中毒抑制的线粒体自噬 (autophagy) 功能。Zeaxanthin dipalmitate 可保护小鼠视网膜中退化的光感受器,可改善感光器变性小鼠模型的视力,可用于酒精性脂肪肝 (AFLD)、色素性视网膜炎 (RP) 的研究。
  • ¥ 1270
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