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A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM).
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 μg | 询价 | 35日内发货 | |
1 mg | 询价 | 35日内发货 | |
5 mg | 询价 | 35日内发货 | |
10 mg | 询价 | 35日内发货 |
产品描述 | A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM). |
分子量 | 140.142 |
分子式 | C6H8N2O2 |
CAS No. | 1331754-16-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
溶解度信息 | PBS (pH 7.2): 10 mg/mL (71.36 mM), Sonication is recommended. DMF: 30 mg/mL (214.07 mM), Sonication is recommended. DMSO: 30 mg/mL (214.07 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMF/DMSO
DMF/DMSO
|
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