MIR96-IN-1

Name: MIR96-IN-1
Brand: TargetMol
SKU: T16077
Price: 228 USD
Availability: InStock
Rating: 4.5 (1 reviews)

产品编号 T16077Cas号 1311982-88-3

MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.

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MIR96-IN-1

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产品编号 T16077Cas号 1311982-88-3

MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.

规格	价格	库存
2 mg	¥ 1,820	5日内发货
5 mg	¥ 2,890	5日内发货
25 mg	¥ 9,620	6-8周
50 mg	¥ 12,500	6-8周
100 mg	¥ 17,500	6-8周
1 mL x 10 mM (in DMSO)	¥ 3,770	5日内发货

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产品介绍

生物活性

产品描述

MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.

体外活性

MIR96-IN-1 inhibits Drosha cleavage of pri-miR-96, as evidenced by an increase in the levels of pri-miR-96 and a reduction in levels of pre- and mature miR-96 in treated cells, as expected if MIR96-IN-1 binds to the Drosha site. MIR96-IN-1 efficiently and selectively silences production of miR-96 at 40 μM while not affecting miR-182 or -183. MIR96-IN-1 inhibits biogenesis of its target precursor miRNA to varying extents: MIR96-IN-1 reduces the expression level of miR-96 by 90% at 40 μM [1].

化学信息

分子量	588.79
分子式	C₃₃H₄₈N₈O₂
CAS No.	1311982-88-3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 100 mg/mL (169.84 mM)

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6984 mL	8.4920 mL	16.9840 mL	84.9199 mL
5 mM	0.3397 mL	1.6984 mL	3.3968 mL	16.9840 mL
10 mM	0.1698 mL	0.8492 mL	1.6984 mL	8.4920 mL
20 mM	0.0849 mL	0.4246 mL	0.8492 mL	4.2460 mL
50 mM	0.0340 mL	0.1698 mL	0.3397 mL	1.6984 mL
100 mM	0.0170 mL	0.0849 mL	0.1698 mL	0.8492 mL