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MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.
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MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 1,820 | 5日内发货 | |
5 mg | ¥ 2,890 | 5日内发货 | |
25 mg | ¥ 9,620 | 6-8周 | |
50 mg | ¥ 12,500 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 | |
1 mL x 10 mM (in DMSO) | ¥ 3,770 | 5日内发货 |
产品描述 | MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells. |
体外活性 | MIR96-IN-1 inhibits Drosha cleavage of pri-miR-96, as evidenced by an increase in the levels of pri-miR-96 and a reduction in levels of pre- and mature miR-96 in treated cells, as expected if MIR96-IN-1 binds to the Drosha site. MIR96-IN-1 efficiently and selectively silences production of miR-96 at 40 μM while not affecting miR-182 or -183. MIR96-IN-1 inhibits biogenesis of its target precursor miRNA to varying extents: MIR96-IN-1 reduces the expression level of miR-96 by 90% at 40 μM [1]. |
分子量 | 588.79 |
分子式 | C33H48N8O2 |
CAS No. | 1311982-88-3 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 100 mg/mL (169.84 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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