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Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
20 μg | ¥ 1,240 | 20日内发货 | |
100 μg | ¥ 2,360 | 20日内发货 | |
1 mg | ¥ 9,870 | 20日内发货 |
生物活性 | Measured by its binding ability in a functional ELISA. Immobilized EDNRB at 5 μg/mL can bind human EDN1 with a linear range of 6.25-25.00 μg/mL. |
产品描述 | Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. |
种属 | Human |
表达系统 | E. coli |
标签 | N-GST |
蛋白编号 | P05305 |
别名 | Preproendothelin-1,PPET1,Endothelin-1,EDN1 |
氨基酸序列 | CSCSSLMDKECVYFCHLDIIW |
蛋白构建 | 53-73 aa |
蛋白纯度 | > 90% as determined by SDS-PAGE. |
分子量 | 29.5 kDa (predicted) |
缓冲液 | Tris-based buffer, 50% glycerol |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. |
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