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Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 462 | 20日内发货 | |
| 10 μg | ¥ 748 | 20日内发货 | |
| 20 μg | ¥ 1,230 | 20日内发货 | |
| 50 μg | ¥ 1,880 | 20日内发货 | |
| 100 μg | ¥ 2,590 | 20日内发货 | |
| 200 μg | ¥ 3,970 | 20日内发货 | |
| 500 μg | ¥ 6,870 | 20日内发货 | |
| 1 mg | ¥ 10,800 | 20日内发货 |
| 生物活性 | Measured by its binding ability in a functional ELISA. Immobilized EDNRB at 5 μg/mL can bind human EDN1 with a linear range of 6.25-25.00 μg/mL. |
| 产品描述 | Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-GST |
| 蛋白编号 | P05305 |
| 别名 | Preproendothelin-1 (PPET1),Endothelin-1,EDN1 |
| 氨基酸序列 | CSCSSLMDKECVYFCHLDIIW |
| 蛋白构建 | 53-73 aa |
| 蛋白纯度 | > 90% as determined by SDS-PAGE. |
| 分子量 | 29.5 kDa (predicted) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 缓冲液 | Tris-based buffer, 50% glycerol |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 研究背景 | Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells. |