CHN1 Protein, Human, Recombinant

产品编号 TMPY-03793

CHN1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 53.2 kDa and the accession number is P15882-1.

CHN1 Protein, Human, Recombinant

产品编号 TMPY-03793

CHN1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 53.2 kDa and the accession number is P15882-1.

规格	价格	库存	数量
100 μg	¥ 4,460	5日内发货

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产品信息

生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	CHN1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 53.2 kDa and the accession number is P15882-1.
种属	Human
表达系统	Baculovirus Insect Cells
标签	Tag Free
蛋白编号	P15882-1
别名	RHOGAP2,NC,DURS2,CHN,chimerin 1,ARHGAP2
蛋白构建	A DNA sequence encoding the human CHN1 (NP_001813.1) (Ala2-Phe459) was fused with two additional amino acids (Gly&Pro) at the N-terminus. Predicted N terminal: Gly
蛋白纯度	> 90 % as determined by SDS-PAGE
分子量	53.2 kDa (predicted); 45 kDa (reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	CHN1, also known as chimerin 1, is a TPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. CHN1 is involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. The CHN1 gene provides instructions for making two very similar proteins called α1-chimaerin and α2-chimaerin. These proteins play an important role in the early development of the nervous system. In particular, they help regulate complex chemical signaling pathways during the formation and development of nerve cells (neurons). These proteins help guide the growth of axons and dendrites, which are specialized extensions of neurons that transmit and receive nerve impulses throughout the nervous system.