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Apoptosisinducer 22 (QR-5),一种引发细胞自我死亡过程(apoptosis)的化合物,主要针对结肠癌细胞系SW480和HT29,其IC50值分别达到63.1和46.5 μM.该化合物通过干扰结肠癌细胞中的Wnt/β-catenin传导轴来激活凋亡机制.因此,Apoptosisinducer 22 是研究抗结肠癌策略的重要工具.
Apoptosisinducer 22 (QR-5),一种引发细胞自我死亡过程(apoptosis)的化合物,主要针对结肠癌细胞系SW480和HT29,其IC50值分别达到63.1和46.5 μM.该化合物通过干扰结肠癌细胞中的Wnt/β-catenin传导轴来激活凋亡机制.因此,Apoptosisinducer 22 是研究抗结肠癌策略的重要工具.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | Apoptosisinducer 22 (QR-5) is a chemical compound that serves as an inducer of apoptosis, exhibiting IC50 values of 63.1 μM for SW480 colon cancer cells and 46.5 μM for HT29 colon cancer cells. It induces apoptosis by inhibiting the Wnt/β-catenin pathway in these cells. Apoptosisinducer 22 is utilized in research targeting colon cancer. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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